Microbial Processing Suite

The Microbial Processing Suite is designed and equipped for producing plasmid DNA and other therapeutics generated from bacterial cells (e.g. recombinant proteins). This suite consists of three interconnected rooms segregating buffer preparation, fermentation and downstream purification/concentration of plasmid or protein products.


Special Features:

  • ISO Class 8 (<352,000 particles/m3, 0.5 micron particles) fermentation room
  • ISO Class 7 (<352,000 particles/m3, 0.5 micron particles) downstream processing room
  • Separate Air Handler Units (AHU) providing single-pass air with terminal HEPA filters
  • Rees Equipment Monitoring System


Select Equipment:

  • Class II Type B3 biosafety cabinets
  • Steam-in-place fermentor with 30 liter working volume
  • Scalable centrifugation system for product recovery
  • Chilled tank and equipment for initial plasmid recovery or protein refolding
  • Scalable Liquid Chromatography (LC) systems
  • Scalable single-use Tangential Flow Filtration (TFF) systems